Levetiracetam-induced pancytopenia

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Levetiracetam-induced pancytopenia

Pancytopenia is a rare side effect of levetiracetam (LEV) that is associated with severe morbidity that requires hospitalization. Here, we report a patient with a right temporoparietal tumor who underwent a temporal craniotomy with resection of the mass and was started on LEV for seizure prophylaxis per the neurosurgery local protocol. The patient developed LEV-induced pancytopenia, which was s...

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Methotrexate Induced Pancytopenia

The well-reported methotrexate (MTX) toxicities are based on the duration and cumulative dosing of drug. The typical toxicities can be predicted by the timing of drug administration, where mucositis occurs as an earlier effect, while myelosuppression and the sequelae of pancytopenia occur later after MTX administration. Despite these well-known toxicities, low dose MTX therapy can become proble...

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Levetiracetam-induced sexual disorders

We read with great interest the article by Metin et al. dealing with the possible correlation between hypersexuality and levetiracetam (LEV). Indeed, the authors reported a female patient with epilepsy who experienced increased sexual drive after the addition of LEV (2000 mg/day) to her ongoing carbamazepine (CBZ) therapy. Although the association between epilepsy and sexual-dysfunction (SD) ha...

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Vancomycin is the first-line agent for the treatment of bacteremia, endocarditis, pneumonia, cellulitis, and osteomyelitis. Pancytopenia is an uncommon adverse effect of vancomycin therapy, with only a few cases of vancomycin-related neutropenia and pancytopenia described in the literature. We describe a case of a 56-year-old man who was diagnosed with chronic paraspinal abscess and started on ...

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Levetiracetam-induced severe acute granulomatous interstitial nephritis

Granulomatous interstitial nephritis (GIN) is an uncommon cause of renal failure, which may be caused by drugs. Levetiracetam is an increasingly used anti-epileptic medication that is not known to cause renal toxicity in adults. To our knowledge, levetiracetam has not previously been reported as a cause of GIN. We report the case of a 69-year-old woman who developed haemodialysis-requiring acut...

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ژورنال

عنوان ژورنال: Epilepsy & Behavior Case Reports

سال: 2015

ISSN: 2213-3232

DOI: 10.1016/j.ebcr.2015.06.001